VAL094
Wilkieson TJ|Khandelwal M|Kotsamanes CZ|Gangji AS|Rabbat CG|Levin A|Madore F|Tobe SW|Moist L|Tonelli M|Soroka SD|Hemmelgarn BR|Lok C|Clase CM
Presented at the Canadian Society of Nephrology Conference in Montreal
OBJECTIVE:
- Volume overload is prevalent in patients with CKD not on dialysis
- Bioimpedance measurements can be interpreted to assess volume status
- The resistance (R) – Reactance (Xc) graph method described by Piccoli and colleagues2 can be operationalized as a dichotomous assessment of volume overload (Figure 1)
- 50% of participants in the CANPREDDICT study will consent to the bioimpedance substudy.
RESULTS:
Participants
- 43% women
- Mean age 66 years
- 34 consecutive CANPREDDICT participants were approached at their first return visit between 2009 December 09 and 2010 April 20
- 28 (82%) participated, 4 declined and 2 deferred their decision to their next visit
- 43% patients volume overloaded by the RXc graph method (Figure 2)
- Kappa was 1.0 for inter-observer agreement in graph interpretation
CONCLUSION:
- The RXc graph method described by Piccoli and colleagues can be reliably operationalized into a dichotomous assessment
- Volume overload according to the RXc method is prevalent in patients with CKD not on dialysis
- The study appears to be feasible
