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Mortality in adult patients with fluid overload.

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Ashuin Kammar-García|Ziv Pérez-Morales|Lilia Castillo-Martinez|José Luis Villanueva-Juárez|Fernanda Bernal-Ceballos|Héctor Isaac Rocha-González| Miguel Remolina-Schlig| Thierry Hernández-Gilsoul.

Postgrad Med J 2018.

Background: The aim of this study was to investigate the association of fluid overload, measured by bioelectrical impedance vector analysis (BIVA) and also by accumulated fluid balance, with 30-day mortality rates in patients admitted to the emergency department (ED).

Subjects and Methods: We conducted a prospective observational study of fluid overload using BIVA, taking measures using a multiple-frequency whole-body tetra polar equipment. Accumulated fluid balances were obtained at 24, 48 and 72 hours from ED admission and its association with 30-day mortality. 109 patients were admitted to the ED classified as fluid overloaded by both methods.

Result and Conclusion: According to BIVA, 71.6% (n=78) of patients had fluid overload on ED admission. These patients were older and had higher Sequential Organ Failure Assessment scores. During a median follow-up period of 30 days, 32.1% (n=25) of patients with fluid overload evaluated by BIVA died versus none with normovolaemia (p=0.001). There was no statistically significant difference in mortality between patients with and without fluid overload as assessed by accumulated fluid balance (p=0.81). Fluid overload on admission evaluated by BIVA was significantly related to mortality in patients admitted to the ED.

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